Gene expression profiling of primary vitreoretinal lymphoma
نویسندگان
چکیده
منابع مشابه
Primary Vitreoretinal Lymphoma Masquerading as Refractory Retinitis
PURPOSE To report a case of a patient with primary vitreoretinal lymphoma masquerading as retinitis. METHODS Retrospective review of the patient's clinical, histopathological and imaging records. RESULTS Cytopathology was negative for malignancy, and preliminary polymerase chain reaction results supported the diagnosis of varicella zoster virus retinitis. Therefore, the patient was treated ...
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Primary CNS lymphoma is an aggressive form of non-Hodgkin lymphoma whose growth is restricted to the central nervous system. We used cDNA microarray analysis to compare the gene expression signature of primary CNS lymphomas with nodal large B-cell lymphomas. Here we show that while individual cases of primary CNS lymphomas may be classified as germinal center B-cell, activated B-cell, or type 3...
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PURPOSE To correlate spectral domain optical coherence tomography (SD-OCT) and photographic imaging before and after spontaneous regression of primary vitreoretinal lymphoma (PVRL) lesions. PROCEDURES We report the case of a 60-year-old female. RESULTS The patient presented with bilateral creamy deposits under the retina and retinal pigment epithelium (RPE), and lesions were visible along B...
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BACKGROUND The prognosis for patients with primary vitreoretinal is dismal. The close association of primary vitreoretinal lymphoma with primary central nervous system lymphoma is responsible for high rates of mortality. Traditional treatments consist of systemic chemotherapy and whole-brain radiotherapy. The optimal approach for the treatment of isolated primary vitreoretinal lymphoma is uncle...
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Primary vitreoretinal lymphoma (PVRL) or primary intraocular lymphoma, a subtype of primary central nervous system lymphoma, often masquerades as uveitis. The diagnosis of PVRL requires identification of lymphoma cells inside the eye, which is often challenging due to the frequent necrosis and admixing of PVRL cells with reactive lymphocytes. Therefore, detection of immunoglobulin heavy chain (...
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ژورنال
عنوان ژورنال: Cancer Science
سال: 2020
ISSN: 1347-9032,1349-7006
DOI: 10.1111/cas.14347